Humans controlled study female human 260 Female 249 article 195 priority journal 181 male 177 Male 174 adult 164 Adult 124 nonhuman 89 human cell 87 Middle Aged 86 Animals 85 Article 76 metabolism 70 protein expression 67 clinical article 62 major clinical study 59 animal experiment 55 aged 52 mouse 52 animal cell 51 Mice 50 Aged 48 animal 47 physiology 47 unclassified drug 44 animal model 40