Clicking Sugars onto Sugars: Oligosaccharide Analogs and Glycoclusters on Carbohydrate Scaffolds

We review herein the recent applications of the copper(I)-catalyzed azide-alkyne cycloaddition to couple carbohydrates and produce compounds of various architectures, molecular weights, and biological properties. The different parts of the chapter correspond to the nature of the products, limited to...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Uhrig, M.L., Kovensky, J.
Formato: CHAP
Materias:
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_97811182_v_n_p107_Uhrig
Aporte de:
Descripción
Sumario:We review herein the recent applications of the copper(I)-catalyzed azide-alkyne cycloaddition to couple carbohydrates and produce compounds of various architectures, molecular weights, and biological properties. The different parts of the chapter correspond to the nature of the products, limited to the examples where carbohydrates are connected by triazol linkers: oligosaccharide analogues, cyclodextrins carrying clicked sugars, macrocyclic analogues, and multivalent glycoclusters on carbohydrate scaffolds. © 2013 John Wiley & Sons, Inc.