Synthesis of Highly Substituted and Enantiomerically Pure 2,3,4-Tris(hydroxyalkyl)pyrrolidines Using a 1,3-Dipolar Cycloaddition Reaction as Key Step

The major endo cycloadducts with a basic structure of methyl 1-aryl-3-(benzyl or methyl)-6-menthyloxy-7-oxooctahydropyrano[4,3-c]pyrrole-3-carboxylate were subjected to simple chemical transformations (mostly reduction and hydrolysis reactions) to afford pyrrolidine bicyclic systems with varied patt...

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Detalles Bibliográficos
Autores principales: Udry, G.A.O., Repetto, E., Vega, D.R., Varela, O.
Formato: JOUR
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Acceso en línea:http://hdl.handle.net/20.500.12110/paper_23656549_v2_n17_p4774_Udry
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