Histone methylation, alternative splicing and neuronal differentiation

Alternative splicing, as well as chromatin structure, greatly contributes to specific transcriptional programs that promote neuronal differentiation. The activity of G9a, the enzyme responsible for mono- and di-methylation of lysine 9 on histone H3 (H3K9me1 and H3K9me2) in mammalian euchromatin, has...

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Detalles Bibliográficos
Autores principales: Fiszbein, A., Kornblihtt, A.R.
Formato: JOUR
Materias:
Alternative splicing
Chromatin modifiers
G9a
H3K9me
Neuronal differentiation
cyclic AMP responsive element binding protein binding protein
histone H3
lysine specific demethylase 1
transcription factor
unclassified drug
alternative RNA splicing
cell differentiation
chromatin structure
embryonic stem cell
euchromatin
gene expression regulation
gene mutation
histone demethylation
histone methylation
human
immunofluorescence
nerve cell differentiation
nonhuman
Note
nuclear localization signal
priority journal
regulatory mechanism
RNA processing
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_23262133_v3_n1_p_Fiszbein
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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