N-acetylcysteine inhibits lipid accumulation in mouse embryonic adipocytes

Oxidative stress plays critical roles in the pathogenesis of diabetes, hypertension, and atherosclerosis; some authors reported that fat accumulation correlates to systemic oxidative stress in human and mice, but cellular redox environment effect on lipid accumulation is still unclear. In our labora...

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Detalles Bibliográficos
Autores principales: Pieralisi, A., Martini, C., Soto, D., Vila, M.C., Calvo, J.C., Guerra, L.N.
Formato: JOUR
Materias:
Adipogenesis
Antioxidants
Kinases
Lipids
MEF
N-acetylcysteine
acetylcysteine
Janus kinase
mitogen activated protein kinase
phosphoERK
phosphoJNK
phosphoprotein
triacylglycerol
unclassified drug
phosphotransferase
adipocyte
adipogenesis
animal cell
animal tissue
antioxidant activity
Article
cell count
cell differentiation
cell function
cell level
cell proliferation
cell stress
cell viability
concentration response
controlled study
disease model
drug cytotoxicity
drug effect
embryo
enzyme phosphorylation
lipid storage
mitotic clonal expansion
mouse
nonhuman
obesity
priority journal
procedures concerning cells
protein expression
protein lipid interaction
signal transduction
3T3-L1 cell line
animal
cytology
drug effects
fibroblast
lipid metabolism
mammalian embryo
metabolism
phosphorylation
3T3-L1 Cells
Acetylcysteine
Adipocytes
Animals
Cell Differentiation
Embryo, Mammalian
Fibroblasts
Lipid Metabolism
Mice
Phosphorylation
Phosphotransferases
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_22132317_v9_n_p39_Pieralisi
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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