Sociability deficits after prenatal exposure to valproic acid are rescued by early social enrichment

Background: Autism spectrum disorder (ASD) is characterized by impaired social interactions and repetitive patterns of behavior. Symptoms appear in early life and persist throughout adulthood. Early social stimulation can help reverse some of the symptoms, but the biological mechanisms of these ther...

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Detalles Bibliográficos
Autores principales: Campolongo, M., Kazlauskas, N., Falasco, G., Urrutia, L., Salgueiro, N., Höcht, C., Depino, A.M.
Formato: JOUR
Materias:
Autism spectrum disorder
Dopamine
Piriform cortex
Sociability
dopamine
protein c fos
valproic acid
adult
adulthood
animal experiment
animal tissue
Article
brain function
controlled study
correlational study
depression
drug effect
female
gestational age
glucose metabolism
habituation
high performance liquid chromatography
immunoreactivity
insula
motor cortex
mouse
nonhuman
positron emission tomography
preclinical study
prenatal exposure
priority journal
progeny
pyriform cortex
social behavior
social disability
social enrichment
social interaction
somatosensory cortex
stimulus response
turnover time
weaning
animal
autism
brain
diagnostic imaging
drug therapy
male
pregnancy
procedures
psychotherapy
Animals
Autism Spectrum Disorder
Brain
Female
Male
Mice
Pregnancy
Prenatal Exposure Delayed Effects
Social Behavior
Socioenvironmental Therapy
Valproic Acid
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_20402392_v9_n1_p_Campolongo
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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