Enhanced Analytical Performance of Paper Microfluidic Devices by Using Fe3O4 Nanoparticles, MWCNT, and Graphene Oxide

Spheres, tubes, and planar-shaped nanomaterials as Fe3O4 nanoparticles (MNPs), multiwalled carbon nanotubes (MWCNT), and graphene oxide (GO) were used for the first time to treat microfluidic paper-based analytical devices (μPADs) and create a biocompatible layer with high catalytic surface. Once gl...

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Detalles Bibliográficos
Autores principales: Figueredo, F., Garcia, P.T., Cortón, E., Coltro, W.K.T.
Formato: JOUR
Materias:
carbon nanotubes
cellulose
clinical diagnostics
colorimetric biosensors
digital image analysis
magnetic nanoparticles
paper microfluidics
Analytic equipment
Biocompatibility
Carbon
Carbon nanotubes
Cellulose
Color
Colorimetric analysis
Colorimetry
Diagnosis
Digital microfluidics
Glucose
Graphene
Microfluidics
Nanomagnetics
Nanoparticles
Nanotubes
Surface treatment
Yarn
Analytical performance
Clinical diagnostics
Colorimetric biosensors
Colorimetric detection
Digital image analysis
Magnetic nano-particles
Micro-fluidic devices
Paper-based analytical devices
Multiwalled carbon nanotubes (MWCN)
Electrical Papers
Iron Compounds
Sensors
carbon nanotube
ferric ion
ferric oxide
glucose
graphite
nanoparticle
chemistry
color
human
lab on a chip
paper
Ferric Compounds
Graphite
Humans
Lab-On-A-Chip Devices
Nanotubes, Carbon
Paper
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_19448244_v8_n1_p11_Figueredo
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
Descripción
Sumario:Spheres, tubes, and planar-shaped nanomaterials as Fe3O4 nanoparticles (MNPs), multiwalled carbon nanotubes (MWCNT), and graphene oxide (GO) were used for the first time to treat microfluidic paper-based analytical devices (μPADs) and create a biocompatible layer with high catalytic surface. Once glucose measurements are critical for diabetes or glycosuria detection and monitoring, the analytical performance of the proposed devices was studied by using bienzymatic colorimetric detection of this carbohydrate. The limit of detection values achieved for glucose with μPADs treated with MNPs, MWCNT, and GO were 43, 62, and 18 μM, respectively. The paper surface modification solves problems associated with the lack of homogeneity on color measurements that compromise the sensitivity and detectability levels in clinical diagnosis. © 2015 American Chemical Society.

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