Altered Peripheral and Central Inflammatory Responses in a Mouse Model of Autism

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Increasing clinical and experimental evidence links immune and inflammatory alterations with the pathogenesis of autism spectrum disorders (ASD). Autistic individuals show signs of neuroinflammation, altered inflammatory responses, and immune abnormalities throughout life. Mice injected subcutaneous...

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Detalles Bibliográficos
Autores principales: Lucchina, L., Depino, A.M.
Formato: JOUR
Materias:
Astroglia
Behavior
Cytokines
Hypothalamus-pituitary-adrenal axis
Microglia
Valproic acid
corticosterone
cytokine
lipopolysaccharide
valproic acid
autacoid
adult
animal experiment
animal model
animal tissue
article
autism
cerebellum
controlled study
corticosterone release
elevated plus maze test
female
glia
hippocampus
male
microglial cell culture
mouse
nervous system inflammation
nonhuman
pathogenesis
priority journal
social interaction
spleen
animal
biological model
blood
chemically induced
immunology
pregnancy
prenatal exposure
real time polymerase chain reaction
Animals
Cerebellum
Child Development Disorders, Pervasive
Corticosterone
Female
Hippocampus
Inflammation Mediators
Lipopolysaccharides
Mice
Models, Genetic
Neuroglia
Pregnancy
Prenatal Exposure Delayed Effects
Real-Time Polymerase Chain Reaction
Valproic Acid
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_19393792_v7_n2_p273_Lucchina
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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