Achieving maximal speed of solution exchange for patch clamp experiments

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Background: Resolving the kinetics of agonist binding events separately from the subsequent channel gating processes requires the ability of applying and removing the agonist before channel gating occurs. No reported system has yet achieved pulses shorter than 100 μs, necessary to study nicotinic AC...

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Detalles Bibliográficos
Autores principales: Auzmendi, J., Fernández Do Porto, D., Pallavicini, C., Moffatt, L.
Formato: JOUR
Materias:
agonist
analytical parameters
article
channel gating
electric potential
flow rate
measurement
oscillation
patch clamp
piezoelectricity
pipette
process optimization
solution exchange system
Electricity
Movement
Patch-Clamp Techniques
Rheology
Solutions
Time Factors
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_19326203_v7_n8_p_Auzmendi
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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