Exploring the nitric oxide detoxification mechanism of mycobacterium tuberculosis truncated haemoglobin N

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Mycobacterium tuberculosis, the causative agent of human tuberculosis, encodes a haemoprotein named Truncated Haemoglobin N (trHbN), which in its active site transforms nitric oxide (NO) to nitrate anion. (NO3 -). The NO-dioxygenase activity of trHbN seems to be crucial for the bacillus, which can s...

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Detalles Bibliográficos
Autores principales: Bidon-Chanal, A., Martí, M.A., Estrín, D.A., Luque, F.J.
Formato: SER
Materias:
Ligand migration
Molecular simulations
Mycobacterium tuberculosis
NO detoxification
Truncated haemoglobin N
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_18746489_v_n_p33_BidonChanal
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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