Regulation of NK cell activation and effector functions by the IL-12 family of cytokines: The case of IL-27

Natural killer (NK) cells are characterized by their ability to detect and induce apoptosis of susceptible target cells and by secretion of immunoregulatory cytokines such as IFN-γ. Activation of these effector functions is triggered upon recognition of tumor and pathogen (mostly virus)-infected cel...

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Detalles Bibliográficos
Autores principales: Zwirner, N.W., Ziblat, A.
Formato: JOUR
Materias:
Cytokines
Cytotoxicity
Dendritic cells
Immunologic
Innate immunity
NK cells
cetuximab
gamma interferon
interleukin 12
interleukin 18
interleukin 23
interleukin 27
rituximab
STAT1 protein
STAT3 protein
trastuzumab
adaptive immunity
antibody dependent cellular cytotoxicity
apoptosis
bone marrow cell
CD4+ T lymphocyte
cell function
cell stimulation
dendritic cell
gene expression
human
immunoregulation
immunosurveillance
immunotherapy
inflammation
innate immunity
lymphocyte activation
macrophage
molecular interaction
natural killer cell
natural killer cell mediated cytotoxicity
nonhuman
Short Survey
tissue injury
upregulation
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_16643224_v8_nJAN_p_Zwirner
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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