Synthesis of encoded modified oligonucleotide libraries part 1 orthogonal chemistry

The basis for further development of combinatorial libraries of modified oligonucleotides tagged by a codifying sequence is discussed. The chemistry involved in the orthogonal synthesis of both strands and some representative examples of building blocks are presented.

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Autores principales: Sacca, P.A., Fontana, A., Montserrat, J.M., Iribarren, A.M.
Formato: JOUR
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Acceso en línea:http://hdl.handle.net/20.500.12110/paper_16121872_v1_n4_p595_Sacca
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