IL17A augments autophagy in Mycobacterium tuberculosis-infected monocytes from patients with active tuberculosis in association with the severity of the disease

During mycobacterial infection, macroautophagy/autophagy, a process modulated by cytokines, is essential for mounting successful host responses. Autophagy collaborates with human immune responses against Mycobacterium tuberculosis (Mt) in association with specific IFNG secreted against the pathogen....

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Detalles Bibliográficos
Autores principales: Tateosian, N.L., Pellegrini, J.M., Amiano, N.O., Rolandelli, A., Casco, N., Palmero, D.J., Colombo, M.I., García, V.E.
Formato: JOUR
Materias:
autophagy
cytokines
IFNG
IL17A
immune response
Mycobacterium tuberculosis
patients
tuberculosis
BCG vaccine
CD14 antigen
gamma interferon
interleukin 17
interleukin 17 receptor
interleukin 17 receptor A
mitogen activated protein kinase 1
mitogen activated protein kinase 14
mitogen activated protein kinase 3
phosphatidylinositol 3 kinase
tuberculostatic agent
unclassified drug
IFNG protein, human
IL17A protein, human
adherent cell
Article
autophagosome
bacterial genome
bacterial growth
bactericidal activity
controlled study
disease classification
disease severity
enzyme activation
human
human cell
intracellular signaling
lung tuberculosis
lysosome
monocyte
peripheral blood mononuclear cell
phagosome
protein phosphorylation
upregulation
cell culture
immunology
microbiology
physiology
signal transduction
Autophagy
Cells, Cultured
Humans
Interferon-gamma
Interleukin-17
Monocytes
Signal Transduction
Tuberculosis
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_15548627_v13_n7_p1191_Tateosian
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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