Efficient production of glycosylated and non-glycosylated mycobacterium tuberculosis antigen 85B fused to PVX coat protein in Nicotiana benthamiana plants

The development of alternative subunit based-vaccines against tuberculosis is necessary due to variable efficiency and some security concerns of the BCG vaccine. The aim of this work was evaluate the production of the Mycobacterium tuberculosis Ag85B antigen fused to Potato Virus X Coat Protein (PVX...

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Detalles Bibliográficos
Autores principales: González, P.A., Puccio, F.D., Zelada, A.M.
Formato: JOUR
Materias:
Ag85B
Agroinfiltration
Molecular pharming
PVX-CP
Tuberculosis
Antigens
Efficiency
Gene expression
Peptides
Plants (botany)
Recombinant proteins
Tubes (components)
Vaccines
Viruses
Silver compounds
ag85b cp
BCG vaccine
fusion protein
gentamicin
glycopeptidase
recombinant protein
rifampicin
unclassified drug
Agrobacterium tumefaciens
amino acid sequence
Article
controlled study
densitometry
DNA sequence
gene
gene sequence
gene silencing
genetic transfection
glycosylation
immunoblotting
molecular cloning
Mycobacterium tuberculosis
Nicotiana benthamiana
nonhuman
plant leaf
plasmid
Potato virus X
protein expression
protein purification
protein synthesis
transgenic plant
transient expression
tuberculosis
Western blotting
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_15533468_v14_n4_p238_Gonzalez
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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