Chromatin, transcript elongation and alternative splicing

A recent study reveals that the chromatin-remodeling factor SWI/SNF regulates alternative splicing by creating internal 'roadblocks' to transcriptional elongation where the phosphorylation status of RNA pol II is qualitatively changed. © 2006 Nature Publishing Group.

Guardado en:
Detalles Bibliográficos
Autor principal: Kornblihtt, A.R.
Formato: JOUR
Materias:
DNA directed RNA polymerase
protein SWI
RNA polymerase II
alternative RNA splicing
chromatin
chromatin assembly and disassembly
genetic transcription
human
phosphorylation
priority journal
protein function
regulatory RNA sequence
short survey
transcription regulation
Alternative Splicing
Animals
Chromatin
Humans
Kinetics
RNA Polymerase II
Transcription Factors
Transcription, Genetic
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_15459993_v13_n1_p5_Kornblihtt
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
Descripción
Sumario:A recent study reveals that the chromatin-remodeling factor SWI/SNF regulates alternative splicing by creating internal 'roadblocks' to transcriptional elongation where the phosphorylation status of RNA pol II is qualitatively changed. © 2006 Nature Publishing Group.

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