Association of HO-1 and BRCA1 is critical for the maintenance of cellular homeostasis in prostate cancer

Prostate cancer is the second leading cause of cancer-related death in men worldwide. Many factors that participate in the development of prostate cancer promote imbalance in the redox state of the cell. Accumulation of reactive oxygen species causes injury to cell structures, ultimately leading to...

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Detalles Bibliográficos
Autores principales: Labanca, E., De Luca, P., Gueron, G., Paez, A., Moiola, C.P., Massillo, C., Porretti, J., Giudice, J., Zalazar, F., Navone, N., Vazquez, E., De Siervi, A.
Formato: JOUR
Materias:
BRCA1 protein
cyclin D1
doxorubicin
etoposide
gelatinase B
heme oxygenase 1
hydrogen peroxide
methotrexate
mitoxantrone
transcription factor Nrf2
BRCA1 protein, human
HMOX1 protein, human
NFE2L2 protein, human
protein binding
animal cell
animal experiment
animal model
Article
cancer cell
controlled study
DNA damage
enzyme mechanism
homeostasis
human
human cell
immunofluorescence
in vitro study
in vivo study
male
mouse
nonhuman
oxidative stress
priority journal
promoter region
prostate cancer
prostate cancer cell line
transcription initiation
transcription regulation
tumor xenograft
animal
genetics
metabolism
pathology
prostate tumor
tumor cell line
xenograft
Animals
BRCA1 Protein
Cell Line, Tumor
DNA Damage
Heme Oxygenase-1
Heterografts
Humans
Male
Mice
NF-E2-Related Factor 2
Oxidative Stress
Prostatic Neoplasms
Protein Binding
Transcriptional Activation
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_15417786_v13_n11_p1455_Labanca
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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