Capturing coevolutionary signals inrepeat proteins

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Background: The analysis of correlations of amino acid occurrences in globular domains has led to the development of statistical tools that can identify native contacts - portions of the chains that come to close distance in folded structural ensembles. Here we introduce a direct coupling analysis f...

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Detalles Bibliográficos
Autores principales: Espada, R., Parra, R.G., Mora, T., Walczak, A.M., Ferreiro, D.U.
Formato: JOUR
Materias:
Co-evolution
Direct coupling analysis
Direct information
Repeat proteins
Amino acids
Statistical mechanics
Confidence levels
Direct coupling
Evolutionary information
Pair correlations
Translational symmetry
Proteins
amino acid
protein
chemistry
human
molecular evolution
molecular model
protein folding
protein motif
protein multimerization
Amino Acid Motifs
Amino Acids
Evolution, Molecular
Humans
Models, Molecular
Protein Folding
Protein Multimerization
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_14712105_v16_n1_p_Espada
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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