Participation Of Eif4F Complex In Junin Virus Infection: Blockage Of Eif4E Does Not Impair Virus Replication

Summary: Translation efficiency of viral mRNAs is a key factor defining both cytopathogenicity and virulence of viruses, which are entirely dependent on the cellular translation machinery to synthesize their proteins. This dependence has led them to develop different translational reprogramming stra...

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Detalles Bibliográficos
Autores principales: Linero, F., Welnowska, E., Carrasco, L., Scolaro, L.
Formato: JOUR
Materias:
2 morpholino 8 phenylchromone
initiation factor 4A
initiation factor 4E
initiation factor 4F
initiation factor 4G
messenger RNA
rapamycin
virus protein
amino terminal sequence
Argentine hemorrhagic fever
article
cellular distribution
comparative study
confocal microscopy
controlled study
cytoplasm
Encephalomyocarditis virus
immunoprecipitation
Junin virus
nonhuman
oxidative stress
Pichinde arenavirus
polyacrylamide gel electrophoresis
priority journal
protein secondary structure
protein synthesis
synthesis
translation initiation
Vero cell
virogenesis
virus culture
virus replication
Arenaviridae
Pichinde virus
Animals
Cercopithecus aethiops
Eukaryotic Initiation Factor-4A
Eukaryotic Initiation Factor-4E
Eukaryotic Initiation Factor-4G
Guanosine
Host-Pathogen Interactions
Nucleocapsid Proteins
Vero Cells
Virus Replication
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_14625814_v15_n10_p1766_Linero
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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