Stereoselective synthesis of 3-deoxy-4-S-(1→4)-thiodisaccharides and their inhibitory activities towards β-glycoside hydrolases
The sulfur linkage of β-(1→4)-thiodisaccharides was constructed with excellent diastereoselectivity by Michael addition of 2,3,4,6-tetra-O- acetyl-1-thio-β-D-galactose (2) or its β-D-glucose isomer (3) to sugar-derived (2S, 6S)-6-acetoxymethyl-2-(2-propyloxy)-2H-pyran-3(6H)-one (1). These reactions...
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| Autores principales: | Uhrig, M.L., Manzano, V.E., Varela, O. |
|---|---|
| Formato: | JOUR |
| Materias: | |
| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_1434193X_v_n1_p162_Uhrig |
| Aporte de: |
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