How does hexachlorobenzene treatment affect liver uroporphyrinogen decarboxylase?

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The aims of the present work were: (1) to investigate whether the strong decrease of liver uroporphyrinogen decarboxylase (UroD) activity observed in experimental porphyria cutanea tarda is due to alteration of the enzymatic protein and (2) to improve the knowledge about the normal liver enzyme. Wit...

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Detalles Bibliográficos
Autores principales: Chaufan, G., Del Carmen Ríos de Molina, M., San Martín de Viale, L.C.
Formato: JOUR
Materias:
Active site
Antigenic determinants
Hexachlorobenzene
Porphyria cutanea tarda
Uroporphyrinogen decarboxylase
cadmium
copper ion
cystine
dithiothreitol
glutathione
hexachlorobenzene
lead
liver enzyme
mercaptoethanol
mercury
uroporphyrinogen decarboxylase
zinc ion
animal experiment
animal model
antigenicity
article
atom
concentration response
controlled study
drug activity
enzyme activity
enzyme analysis
enzyme binding
enzyme conformation
enzyme inhibition
hydration
nonhuman
pH
physical chemistry
porphyria cutanea tarda
rat
Animals
Antigens
Female
Fungicides, Industrial
Hydrogen-Ion Concentration
Liver
Rats
Rats, Wistar
Temperature
Uroporphyrinogen Decarboxylase
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_13572725_v33_n6_p621_Chaufan
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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