FKBP51 and FKBP52 in signaling and disease

FKBP51 and FKBP52 are diverse regulators of steroid hormone receptor signaling, including receptor maturation, hormone binding and nuclear translocation. Although structurally similar, they are functionally divergent, which is largely attributed to differences in the FK1 domain and the proline-rich...

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Detalles Bibliográficos
Autores principales: Storer, C.L., Dickey, C.A., Galigniana, M.D., Rein, T., Cox, M.B.
Formato: JOUR
Materias:
androgen receptor
antineoplastic agent
doxorubicin
estrogen receptor
immunoglobulin enhancer binding protein
mineralocorticoid receptor
multiprotein complex
progesterone receptor
protein FKBP51
protein FKBP52
protein kinase B
receptor chaperone complex
regulator protein
steroid hormone
steroid receptor
tacrolimus
unclassified drug
Alzheimer disease
anxiety disorder
bipolar disorder
breast carcinogenesis
breast tumor
cell proliferation
cellular distribution
complex formation
depression
disease association
drug targeting
genital system
human
immune system
immunopathology
mental stress
metabolic disorder
molecular pathology
neuropathology
nonhuman
pathophysiology
posttraumatic stress disorder
priority journal
prostate cancer
protein conformation
protein folding
protein function
protein localization
protein protein interaction
protein structure
review
schizophrenia
signal transduction
tauopathy
Alzheimer Disease
Animals
Humans
Molecular Chaperones
Molecular Targeted Therapy
Neoplasms
Protein Transport
Receptors, Steroid
Signal Transduction
Stress, Psychological
Tacrolimus Binding Proteins
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_10432760_v22_n12_p481_Storer
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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