An antiviral principle present in a purified fraction from Melia azedarach L. leaf aqueous extract restrains herpes simplex virus type 1 propagation

Meliacine (MA), an antiviral principle isolated from leaves of Melia azedarach L., exhibits potent antiviral activity against herpes simplex virus type 1 (HSV-1) by inhibiting specific infected-cell polypeptides (ICPs) produced late in infection. Some of these are involved in DNA synthesis and in th...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Alché, L.E., Barquero, A.A., Sanjuan, N.A., Coto, C.E.
Formato:	JOUR
Materias:	Antiviral Herpes simplex virus type 1 Melia azedarach L. Meliacine antivirus agent beta galactosidase meliacine polypeptide unclassified drug virus DNA animal cell antiviral activity aqueous solution article controlled study cytoplasm cytoplasm vesicle DNA cleavage DNA packaging DNA synthesis drug mechanism drug synthesis enzyme activity Herpes simplex virus 1 medicinal plant melia azedarach molecular weight nonhuman plant leaf time Vero cell virus envelope virus inhibition virus nucleocapsid virus particle virus replication Animals Antiviral Agents Cell Transformation, Viral Cercopithecus aethiops DNA, Viral Herpesvirus 1, Human Meliaceae Plant Extracts Plant Leaves Vero Cells Viral Proteins Virus Replication Human herpesvirus 1 Melia azedarach Simplexvirus
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_0951418X_v16_n4_p348_Alche
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

Ejemplares similares

An antiviral principle present in a purified fraction from Melia azedarach L. leaf aqueous extract restrains herpes simplex virus type 1 propagation
por: Alche, Laura Edith, et al.
Publicado: (2002)

Antiviral effects of Melia azedarach L. leaves extracts on Sindbis virus-infected cells
por: Wachsman, Mónica Beatriz, et al.
Publicado: (1987)

Antiviral effects of Melia azedarach L. leaves extracts on Sindbis virus-infected cells
por: Wachsman, M.B., et al.

Antiviral activity of meliacine on the replication of a thymidine kinase-deficient mutant of Herpes simplex virus type 1 alone and in combination with acyclovir
Publicado: (1997)

Antiviral activity of meliacine on the replication of a thymidine kinase-deficient mutant of Herpes simplex virus type 1 alone and in combination with acyclovir
por: Barquero, A.A., et al.

Induction of a refractory state to viral infection in mammalian cells by a plant inhibitor isolated from leaves of Melia azedarach L
por: Andrei, Graciela Mónica, et al.
Publicado: (1988)

Induction of a refractory state to viral infection in mammalian cells by a plant inhibitor isolated from leaves of Melia azedarach L
por: Andrei, G.M., et al.

Inhibition of herpes simplex virus type-1 multiplication by meliacine, a peptide of plant origin
por: Alche, Laura Edith, et al.
Publicado: (1995)

Inhibition of herpes simplex virus type-1 multiplication by meliacine, a peptide of plant origin
por: Villamil, S.M., et al.

Natural resistance of BALB/c mice to herpes simplex virus-type 1 intraperitoneal infection is abrogated by a plant extract with in vitro anti- herpes activity
Publicado: (1998)

Natural resistance of BALB/c mice to herpes simplex virus-type 1 intraperitoneal infection is abrogated by a plant extract with in vitro anti- herpes activity
por: Claus, J.D., et al.

Treatment with meliacine, a plant derived antiviral, prevents the development of herpetic stromal keratitis in mice
Publicado: (2000)

Treatment with meliacine, a plant derived antiviral, prevents the development of herpetic stromal keratitis in mice
por: Alché, L.E., et al.

Therapeutic effect of meliacine, an antiviral derived from Melia azedarach L., in mice genital herpetic infection
Publicado: (2009)

Therapeutic effect of meliacine, an antiviral derived from Melia azedarach L., in mice genital herpetic infection
por: Petrera, E., et al.

An antiviral meliacarpin from leaves of Melia azedarach L.
Publicado: (2003)

An antiviral meliacarpin from leaves of Melia azedarach L.
por: Alché, L.E., et al.

1-Cinnamoyl-3,11-dihydroxymeliacarpin delays glycoprotein transport restraining virus multiplication without cytotoxicity
por: Bueno, Carlos Alberto, et al.
Publicado: (2010)

1-Cinnamoyl-3,11-dihydroxymeliacarpin delays glycoprotein transport restraining virus multiplication without cytotoxicity
por: Bueno, C.A., et al.

Inhibition of Pseudorabies virus multiplication by an antiviral isolated from Melia azedarach L green leaves
por: Descalzo, Adriana María, et al.
Publicado: (1989)

Inhibition of Pseudorabies virus multiplication by an antiviral isolated from Melia azedarach L green leaves
por: Descalzo, A.M., et al.

1-Cinnamoyl-3,11-dihydroxymeliacarpin is a natural bioactive compound with antiviral and nuclear factor-κB modulating properties
por: Barquero, Andrea Alejandra, et al.
Publicado: (2006)

1-Cinnamoyl-3,11-dihydroxymeliacarpin is a natural bioactive compound with antiviral and nuclear factor-κB modulating properties
por: Barquero, A.A., et al.

Antiviral activity of sandalwood oil against Herpes simplex viruses-1 and -2
Publicado: (1999)

Antiviral activity of sandalwood oil against Herpes simplex viruses-1 and -2
por: Benencia, F., et al.

Antiviral effect of brassinosteroids against herpes virus and arenaviruses
por: Wachsman, Mónica Beatriz, et al.
Publicado: (2000)

Antiviral effect of brassinosteroids against herpes virus and arenaviruses
por: Wachsman, M.B., et al.

Therapeutic action of meliacine, a plant-derived antiviral, on HSV-induced ocular disease in mice
por: Pifarré, María Paula, et al.
Publicado: (2002)

Therapeutic action of meliacine, a plant-derived antiviral, on HSV-induced ocular disease in mice
por: Paula Pifarré, M., et al.

Antiviral activity of natural sulphated galactans on herpes virus multiplication in cell culture
por: Carlucci, María Josefina, et al.
Publicado: (1997)

Antiviral activity of natural sulphated galactans on herpes virus multiplication in cell culture
por: Carlucci, M.J., et al.

Herpes simplex virus-inhibitory sulfated xylogalactans from the red seaweed Nothogenia fastigiata
por: Damonte, Elsa Beatriz, et al.
Publicado: (1996)

Herpes simplex virus-inhibitory sulfated xylogalactans from the red seaweed Nothogenia fastigiata
por: Damonte, E.B., et al.

Effective treatment of mouse herpetic stromal keratitis with meliacine, a plant-derived antiviral
por: Alche, Laura Edith, et al.
Publicado: (2001)

Effective treatment of mouse herpetic stromal keratitis with meliacine, a plant-derived antiviral
por: Alché, L.E., et al.

Inhibitory action of natural carrageenans on herpes simplex virus infection of mouse astrocytes
Publicado: (1999)

Inhibitory action of natural carrageenans on herpes simplex virus infection of mouse astrocytes
por: Carlucci, M.J., et al.

Synthetic pregnenolone derivatives as antiviral agents against acyclovir-resistant isolates of Herpes Simplex Virus Type 1
por: Alche, Laura Edith, et al.
Publicado: (2015)

Synthetic pregnenolone derivatives as antiviral agents against acyclovir-resistant isolates of Herpes Simplex Virus Type 1
por: Dávola, M.E., et al.

Virucidal activity in aqueous extracts obtained from Cedrela tubiflora leaves
por: Coto, Celia Esther, et al.
Publicado: (1991)