Activation of ErbB-2 via a hierarchical interaction between ErbB-2 and type I insalia-like growth factor receptor in mammary tumor cells

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The present study focused on interactions between signaling pathways activated by progestins and by type I and II receptor tyrosine kinases (RTKs) in mammary tumors. An experimental model in which the synthetic progestin medroxyprogesterone acetate (MPA) induced mammary adenocarcinomas in Balb/c mic...

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Detalles Bibliográficos
Autores principales:	Balãá, M.E., Labriola, L., Salatino, M., Movsichoff, F., Peters, G., Charreau, E.H., Elizalde, P.V.
Formato:	JOUR
Materias:	ErbB receptors Mammary tumorigenesis Progestin Type I insulin-like growth factor receptor antisense oligodeoxynucleotide gestagen medroxyprogesterone acetate messenger RNA neu differentiation factor oligomer protein tyrosine kinase somatomedin C receptor animal cell animal experiment animal model animal tissue article breast carcinogenesis breast epithelium breast tumor cell proliferation complex formation confocal laser microscopy controlled study female gene activation mouse nonhuman oncogene neu priority journal protein localization protein phosphorylation protein protein interaction signal transduction Animals Enzyme Activation Epithelial Cells Female Macromolecular Substances Mammary Neoplasms, Experimental Medroxyprogesterone 17-Acetate Mice Mice, Inbred BALB C Oligodeoxyribonucleotides, Antisense Phosphorylation Progesterone Congeners Receptor Cross-Talk Receptor, erbB-2 Receptor, IGF Type 1 Signal Transduction Tumor Cells, Cultured Tyrosine Animalia Mink cell focus-forming virus
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_09509232_v20_n1_p34_Balaa
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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