Interleukin-6 is inhibited by glucocorticoids and stimulates ACTH secretion and POMC expression in human corticotroph pituitary adenomas

Interleukins and their receptors are expressed intrinsically in the anterior pituitary and regulate hormone production and cell proliferation. It has previously been shown that interleukin-6 (IL-6) regulates hormone secretion in normal pituitary cells and cell lines. Here we examined the effects of...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Páez Pereda, M., Lohrer, P., Kovalovsky, D., Perez Castro, C., Goldberg, V., Losa, M., Chervín, A., Berner, S., Molina, H., Stalla, G.K., Renner, U., Arzt, E.
Formato:	JOUR
Materias:	ACTH Corticotroph adenoma Interleukin-6 Proopiomelanocortin corticotropin dexamethasone interleukin 6 proopiomelanocortin adult article clinical article controlled study cytokine release female gene expression hormone release human human cell human tissue hypophysis tumor male priority journal Adenoma Adrenocorticotropic Hormone Adult Cushing Syndrome Female Gene Expression Regulation, Neoplastic Humans Male Middle Aged Pituitary Neoplasms Pro-Opiomelanocortin Recombinant Proteins RNA, Messenger Transcription, Genetic Tumor Cells, Cultured
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_09477349_v108_n3_p202_PaezPereda
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

Ejemplares similares

Interleukin-6 is inhibited by glucocorticoids and stimulates ACTH secretion and POMC expression in human corticotroph pituitary adenomas
por: Páez Pereda, Marcelo, et al.
Publicado: (2000)

Interleukin-2 (IL-2) and IL-6 regulate c-fos protooncogene expression in human pituitary adenoma explants
por: Páez Pereda, M., et al.

Interleukin-2 (IL-2) and IL-6 regulate c-fos protooncogene expression in human pituitary adenoma explants
por: Páez Pereda, Marcelo
Publicado: (1996)

Interleukin-1β enhances interleukin-1 receptor antagonist content in human somatotroph adenoma cell cultures
Publicado: (1998)

Interleukin-1β enhances interleukin-1 receptor antagonist content in human somatotroph adenoma cell cultures
por: Sauer, J., et al.

Estradiol Stimulates Vascular Endothelial Growth Factor and Interleukin-6 in Human Lactotroph and Lactosomatotroph Pituitary Adenomas
por: Onofri, C., et al.

Estradiol Stimulates Vascular Endothelial Growth Factor and Interleukin-6 in Human Lactotroph and Lactosomatotroph Pituitary Adenomas
por: Carbia Nagashima, Alberto Nicolás
Publicado: (2004)

Functional in vitro studies on the role and regulation of interleukin-6 in human somatotroph pituitary adenomas
por: Thiele, J.-O., et al.

Functional in vitro studies on the role and regulation of interleukin-6 in human somatotroph pituitary adenomas
Publicado: (2003)

Molecular Mechanisms Underlying Pituitary Pathogenesis
Publicado: (2016)

Molecular Mechanisms Underlying Pituitary Pathogenesis
por: Sapochnik, M., et al.

Pathophysiological role of the cytokine network in the anterior pituitary gland
por: Páez Pereda, Marcelo, et al.
Publicado: (1999)

Pathophysiological role of the cytokine network in the anterior pituitary gland
por: Arzt, E., et al.

Cytokines and genes in pituitary tumorigenesis: RSUME role in cell biology
por: Gerez, Juan Atilio, et al.
Publicado: (2010)

Cytokines and genes in pituitary tumorigenesis: RSUME role in cell biology
por: Fuertes, M., et al.

VEGF and CD31 association in pituitary adenomas
por: Cristina, C., et al.

Effects of the gp130 cytokines ciliary neurotropic factor (CNTF) and interleukin-11 on pituitary cells: CNTF receptors on human pituitary adenomas and stimulation of prolactin and GH secretion in normal rat anterior pituitary aggregate cultures
por: Perez Castro, C., et al.

Differential regulation of interleukin-1 receptor antagonist by proopiomelanocortin peptides adrenocorticotropic hormone and β-endorphin
por: Kovalovsky, Damián, et al.
Publicado: (1999)

VEGF and CD31 association in pituitary adenomas
Publicado: (2010)

Effects of the gp130 cytokines ciliary neurotropic factor (CNTF) and interleukin-11 on pituitary cells: CNTF receptors on human pituitary adenomas and stimulation of prolactin and GH secretion in normal rat anterior pituitary aggregate cultures
Publicado: (2001)

Differential regulation of interleukin-1 receptor antagonist by proopiomelanocortin peptides adrenocorticotropic hormone and β-endorphin
por: Kovalovsky, D., et al.

Corticotropin-releasing hormone differentially modulates the interleukin-1 system according to the level of monocyte activation by endotoxin
Publicado: (1995)

Corticotropin-releasing hormone differentially modulates the interleukin-1 system according to the level of monocyte activation by endotoxin
por: Pereda, M.P., et al.

Insulin effect on interleukin 1 (IL-1) and interleukin 6 (IL-6) production by lipopolysaccharide-stimulated human monocytes
Publicado: (1994)

Insulin effect on interleukin 1 (IL-1) and interleukin 6 (IL-6) production by lipopolysaccharide-stimulated human monocytes
por: Schillaci, R., et al.

Programmed cell senescence: Role of IL-6 in the pituitary
Publicado: (2017)

Programmed cell senescence: Role of IL-6 in the pituitary
por: Sapochnik, M., et al.

Influence of zinc administered by total parenteral nutrition on plasmatic zinc levels, on reactive C protein, on serum interleukin-6 and on serum interleukin-6 soluble receptor, in critical patients
por: Zeni, Susana Noemí
Publicado: (2009)

Influence of zinc administered by total parenteral nutrition on plasmatic zinc levels, on reactive C protein, on serum interleukin-6 and on serum interleukin-6 soluble receptor, in critical patients
por: Menéndez, A.Ma., et al.

Human granulosa cells express HLA-DR antigen and are capable of synthesizing interleukin-1
Publicado: (1995)

Human granulosa cells express HLA-DR antigen and are capable of synthesizing interleukin-1
por: Baranao, R.I., et al.

Determination of IL-1 and IL-6 levels in human embryo culture-conditioned media
Publicado: (1997)

Determination of IL-1 and IL-6 levels in human embryo culture-conditioned media
por: Barañao, R.I., et al.

Autocrine IL-6 mediates pituitary tumor senescence
por: Haedo, Mariana Raquel
Publicado: (2017)

Autocrine IL-6 mediates pituitary tumor senescence
por: Sapochnik, M., et al.

Effect of leptin on progesterone, human chorionic gonadotropin, and interleukin-6 secretion by human term trophoblast cells in culture
Publicado: (2003)

Effect of leptin on progesterone, human chorionic gonadotropin, and interleukin-6 secretion by human term trophoblast cells in culture
por: Cameo, P., et al.

Clinical characteristics and therapeutic responses in patients with germ-line AIP mutations and pituitary adenomas: An international collaborative study
Publicado: (2010)

Clinical characteristics and therapeutic responses in patients with germ-line AIP mutations and pituitary adenomas: An international collaborative study
por: Daly, A.F., et al.

Long-term intracerebroventricular corticotropin-releasing hormone administration induces distinct changes in rat splenocyte activation and cytokine expression
por: Labeur, Marta Susana
Publicado: (1995)