Effects of staurosporine on ACTH-mediated stimulation of aldosterone production

Incubation of rat adrenal glomerulosa cells with low concentrations (up to 50 nM) of the protein kinase (PKC) inhibitor staurosporine (ST) inhibited aldosterone (ALDO) and cyclic AMP (cAMP) production stimulated by adrenocorticotropic hormone (ACTH) and cholera toxin. Only higher concentrations (1.6...

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Autores principales: Pecci, A., Romero, D.G., Gomez-Sanchez, C.E., Lantos, C.P., Cozza, E.N.
Formato: JOUR
Materias:
rat
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_08986568_v8_n5_p381_Pecci
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