C/EBP2 mediates growth hormone-regulated expression of multiple target genes

Regulation of c-Fos transcription by GH is mediated by CCAAT/enhancer binding protein β (C/EBPβ). This study examines the role of C/EBPβ in mediating GH activation of other early response genes, including Cyr61, Btg2, Socs3, Zfp36, and Socs1. C/EBPβ depletion using short hairpin RNA impaired respons...

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Detalles Bibliográficos
Autores principales:	Cui, T.X., Lin, G., Lapensee, C.R., Calinescu, A.-A., Rathore, M., Streeter, C., Piwien-Pilipuk, G., Lanning, N., Jin, H., Carter-Su, C., Qin, Z.S., Schwartz, J.
Formato:	JOUR
Materias:	CCAAT enhancer binding protein beta cyclic AMP responsive element binding protein growth hormone mitogen activated protein kinase protein p300 short hairpin RNA STAT protein 1,3 butadiene derivative 1,4 diamino 1,4 bis(2 aminophenylthio) 2,3 dicyanobutadiene Cebpb protein, mouse histone acetyltransferase PCAF nitrile small interfering RNA animal cell article early response gene enzyme activation gene activation gene expression gene expression regulation gene targeting human human cell mouse nonhuman oncogene c fos priority journal promoter region protein phosphorylation animal cell line chromatin immunoprecipitation Cricetulus DNA responsive element genetics hamster immunoblotting metabolism mutation oncogene phosphorylation polymerase chain reaction signal transduction transcription initiation Animals Butadienes CCAAT-Enhancer-Binding Protein-beta Cell Line Chromatin Immunoprecipitation Cricetinae Extracellular Signal-Regulated MAP Kinases Gene Expression Regulation Genes, fos Growth Hormone Immunoblotting Mice Mutation Nitriles p300-CBP Transcription Factors Phosphorylation Polymerase Chain Reaction Promoter Regions, Genetic Response Elements RNA, Small Interfering Signal Transduction Transcriptional Activation
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_08888809_v25_n4_p681_Cui
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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