Antimalarial activity of new acridinone derivatives

Malaria is one of the major threats concerning world public health. Resistance to the current antimalarial drugs has led to searches for new antimalarial compounds. Acridinone derivatives have recently demonstrated to be active against malaria parasite. We focused our attention on synthesized new ac...

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Detalles Bibliográficos
Autores principales: Fernández-Calienes, A., Pellón, R., Docampo, M., Fascio, M., D'Accorso, N., Maes, L., Mendiola, J., Monzote, L., Gille, L., Rojas, L.
Formato: JOUR
Materias:
Acridinone
Antimalarial activity
Plasmodium falciparum
10 (1,2 propadienyl) 9 (10h) acridinone
10 (3 methyl 2 butenyl) 9 (10h) acridinone
10 allyl 9 (10h) acridinone
antimalarial agent
atovaquone
beta hematin
chloroquine
heme derivative
stigmatellin
unclassified drug
animal cell
antimalarial activity
article
controlled study
cow
cytotoxicity
drug selectivity
heart muscle cell
human
human cell
IC 50
nonhuman
priority journal
spectrophotometry
yeast
Acridines
Animals
Antimalarials
Cattle
Cell Line
Drug Resistance, Microbial
Hemeproteins
Humans
Malaria
Yeasts
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_07533322_v65_n3_p210_FernandezCalienes
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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