Diurnal Variations of Benzodiazepine Binding in Rat Cerebral Cortex: Disruption by Pinealectomy

In a previous work, pinealectomy was found to depress benzodiazepine (BZP) receptor binding in cerebral cortex membranes of rats killed at noon. In order to assess the effect of pineal removal on diurnal variations of BZP binding site concentration and affinity, groups of intact, pinealectomized, or...

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Detalles Bibliográficos
Autores principales:	Acuña‐Castroviejo, D., Lowenstein, P.R., Rosenstein, R., Cardinali, D.P.
Formato:	JOUR
Materias:	brain benzodiazepine binding diurnal rhythms melatonin pineal gland pinealectomy benzodiazepine receptor flunitrazepam radioisotope animal cell animal experiment autopsy brain cortex central nervous system circadian rhythm drug administration drug binding drug receptor binding flunitrazepam h 3 methodology nonhuman pharmacokinetics rat Animal Cerebral Cortex Circadian Rhythm Dose-Response Relationship, Drug Flunitrazepam Male Melatonin Membranes Pineal Gland Rats Receptors, GABA-A Support, Non-U.S. Gov't
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_07423098_v3_n2_p101_Acuna‐Castroviejo
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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