Biosynthesis of progesterone derived neurosteroids by developing avian CNS : In vitro effects on the gabaa receptor complex

It has been demonstrated in different vertebrate species that the GABA(A) receptor complex is modulated by certain steroids. Theses results prompted work on the synthesis of these neurosteroids in the Central Nervous System. However, there are scarcely any studies analyzing their production or their...

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Detalles Bibliográficos
Autores principales: Pignataro, L., Colman Lerner, A.A., Barañao, J.L., De Plazas, S.F.
Formato: JOUR
Materias:
Chick optic lobe
Developing avian CNS
GABA(A) receptor complex
Neurosteroidogenesis
Neurosteroids
[C]Progesterone
[H]Flunitrazepam binding modulation
3beta hydroxy 5beta pregnan 20 one
4 aminobutyric acid A receptor
carbon 14
flunitrazepam
neurosteroid
pregnanedione
progesterone
animal tissue
article
binding affinity
biosynthesis
central nervous system
chicken
controlled study
embryo
fowl
nervous system development
nonhuman
optic lobe
priority journal
steroid metabolism
steroidogenesis
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_07365748_v16_n5_p433_Pignataro
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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