Involvement of hnRNP A1 in the matrix metalloprotease-3-dependent regulation of Rac1 pre-mRNA splicing

Rac1b is an alternatively spliced isoform of the small GTPase Rac1 that includes the 57-nucleotide exon 3b. Rac1b was originally identified through its over-expression in breast and colorectal cancer cells, and has subsequently been implicated as a key player in a number of different oncogenic signa...

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Detalles Bibliográficos
Autores principales: Pelisch, F., Khauv, D., Risso, G., Stallings-Mann, M., Blaustein, M., Quadrana, L., Radisky, D.C., Srebrow, A.
Formato: JOUR
Materias:
alternative splicing
hnrnp
matrix metalloprotease
Rac1
heterogeneous nuclear ribonucleoprotein
heterogeneous nuclear ribonucleoprotein A1
messenger RNA
Rac1 protein
stromelysin
unclassified drug
animal cell
article
cell transformation
controlled study
exon
human
human tissue
mouse
nonhuman
priority journal
protein binding
protein expression
protein secretion
proteomics
RNA splicing
signal transduction
Alternative Splicing
Animals
Cell Line, Tumor
Epithelial Cells
Female
Heterogeneous-Nuclear Ribonucleoprotein Group A-B
Mammary Glands, Animal
Mammary Neoplasms, Animal
Matrix Metalloproteinase 3
Mice
Neuropeptides
Protein Isoforms
Proteomics
rac GTP-Binding Proteins
RNA Precursors
RNA Splicing
RNA, Messenger
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_07302312_v113_n7_p2319_Pelisch
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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