Antiviral activity of an acidic polysaccharides fraction extracted from Cedrela tubiflora leaves

An acidic polysaccharides fraction (APS) obtained from Cedrela tubiflora leaves was tested for antiviral activity. This fraction inhibited the replication of HSV-2 and VSV, while the replication of poliovirus was not affected. APS was not virucidal, but no cytotoxicity was present in the different c...

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Detalles Bibliográficos
Autores principales: Craig, M.I., Benencia, F., Coulombié, F.C.
Formato: JOUR
Materias:
Antiviral activity
Cedrela tubiflora
Polysaccharides
antivirus agent
cedrela terminalis extract
plant extract
polysaccharide
unclassified drug
animal cell
antiviral activity
article
cedrela tubiflora
cell culture
controlled study
cytotoxicity
drug isolation
drug screening
Herpes simplex virus 2
in vitro study
nonhuman
phytochemistry
plant leaf
Poliomyelitis virus
Vero cell
Vesicular stomatitis virus
virus adsorption
Cedrela
Human herpesvirus 2
Poliovirus
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_0367326X_v72_n2_p113_Craig
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
Descripción
Sumario:An acidic polysaccharides fraction (APS) obtained from Cedrela tubiflora leaves was tested for antiviral activity. This fraction inhibited the replication of HSV-2 and VSV, while the replication of poliovirus was not affected. APS was not virucidal, but no cytotoxicity was present in the different concentrations of APS assayed. Copyright © 2001 Elsevier Science B.V.

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