Influence] of enzymatic treatment on Junin virus--Vero cells interaction

The chemical nature of cellular structures involved in the attachment of Junin virus (wild type XJC13 and host range mutant Cl 67) to Vero cells was investigated. Enzyme treatment of cells before virus infection indicated that whereas lipids are not directly involved in virus attachment, cellular pr...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Raiger Iustman, L.J., Candurra, N., Mersich, S.E.
Formato: JOUR
Materias:
enzyme
animal
article
cell culture
Cercopithecus
drug effect
female
Junin virus
male
physiology
Vero cell
virology
Animals
Cells, Cultured
Cercopithecus aethiops
Enzymes
Female
Male
Vero Cells
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_03257541_v27_n1_p28_RaigerIustman
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
Descripción
Sumario:The chemical nature of cellular structures involved in the attachment of Junin virus (wild type XJC13 and host range mutant Cl 67) to Vero cells was investigated. Enzyme treatment of cells before virus infection indicated that whereas lipids are not directly involved in virus attachment, cellular proteins play a significant role in early interaction with JV. Moreover aromatic residues, leucine and basic amino acid seem to actively participate in this interaction with different affinity for the assayed strains.

Ejemplares similares