Long-term memory consolidation depends on proteasome activity in the crab Chasmagnathus

Long-term memory formation depends on protein and mRNA synthesis that subserves synaptic reorganization. The removal of pre-existing inhibitory proteins by the ubiquitin-proteasome system (UPS) is proposed as a crucial step to support these modifications. The activation of the constitutive transcrip...

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Detalles Bibliográficos
Autores principales: Merlo, E., Romano, A.
Formato: JOUR
Materias:
consolidation
long-term memory
MG132
NF-κB
transcription factor
ubiquitin-proteasome system
benzyloxycarbonylleucylleucylleucinal
I kappa B
immunoglobulin enhancer binding protein
proteasome
ubiquitin
animal experiment
article
controlled study
crab
drug effect
drug inhibition
long term memory
male
nonhuman
priority journal
short term memory
Animals
Brachyura
Conditioning, Classical
Cysteine Proteinase Inhibitors
Dose-Response Relationship, Drug
Leupeptins
Male
Memory
Motor Activity
Neuronal Plasticity
NF-kappa B
Proteasome Endopeptidase Complex
Time Factors
Ubiquitin
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_03064522_v147_n1_p46_Merlo
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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