When size does matter: Organelle size influences the properties of transport mediated by molecular motors

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Background Organelle transport is driven by the action of molecular motors. In this work, we studied the dynamics of organelles of different sizes with the aim of understanding the complex relation between organelle motion and microenvironment. Methods We used single particle tracking to obtain traj...

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Detalles Bibliográficos
Autores principales: De Rossi, M.C., Bruno, L., Wolosiuk, A., Despósito, M.A., Levi, V.
Formato: JOUR
Materias:
Intracellular transport
Molecular motors
Organelle trafficking
Single particle tracking
Xenopus laevis melanophores-
actin
molecular motor
animal cell
article
cell aggregation
cell tracking
cell transport
controlled study
depolymerization
diffusion
dispersion
intermediate filament
melanosome
nonhuman
organelle size
priority journal
Xenopus laevis
anomalous diffusion exponent
DLS
dynamic light scattering
FE-SEM
field emission-scanning electron microscopy
IF
intermediate filaments
mean square displacement
MSD
optical radius
OR
Xenopus laevis melanophores
α
Actins
Animals
Biological Transport
Cells, Cultured
Cellular Microenvironment
Diffusion
Dyneins
Intermediate Filaments
Melanophores
Melanosomes
Microtubules
Molecular Motor Proteins
Organelle Size
Organelles
Structure-Activity Relationship
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_03044165_v1830_n11_p5095_DeRossi
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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