Angiopoietin 1 reduces rat follicular atresia mediated by apoptosis through the PI3K/Akt pathway

The aim of this study was to determine the effect of the local inhibition of ANGPT1 on steroid production, proliferation and apoptosis of ovarian follicular cells and on the PI3K/AKT pathway. We also examined the effect of ANGPTs on follicular cell apoptosis and proliferation in early antral follicl...

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Detalles Bibliográficos
Autores principales: Parborell, F., Abramovich, D., Irusta, G., Tesone, M.
Formato: JOUR
Materias:
Angiogenesis
Angiopoietins
Apoptosis
Follicular development
Ovary
actin
androsterone
angiopoietin 1
angiopoietin 2
antibody
caspase 3
cycline
diethylstilbestrol
estradiol
phosphatidylinositol 3 kinase
protein kinase B
animal cell
animal experiment
animal tissue
antigen expression
apoptosis
article
cell proliferation
controlled study
enzyme phosphorylation
female
nonhuman
ovary follicle atresia
ovary follicle cell
prepuberty
priority journal
protein function
rat
steroidogenesis
Angiopoietin-1
Animals
Caspase 3
Cell Proliferation
Cells, Cultured
Female
Follicular Atresia
Humans
Ovarian Follicle
Phosphatidylinositol 3-Kinases
Proto-Oncogene Proteins c-akt
Rats
Rats, Sprague-Dawley
Signal Transduction
Steroids
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_03037207_v343_n1-2_p79_Parborell
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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