Phenotypic characterisation of mice with exaggerated and missing LH/hCG action

In order to study the physiology and pathophysiology of gonadotrophin action, we have produced transgenic (TG) mice overexpressing human chorionic gonadotrophin (hCG) α and β subunits (hCG+ mice) and knockout (KO) mice for the luteinising hormone receptor (LHR; LuRKO mice). The two extremes in LH fu...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Ahtiainen, P., Rulli, S., Pakarainen, T., Zhang, F.-P., Poutanen, M., Huhtaniemi, I.
Formato:	JOUR
Materias:	Knockout Luteinising hormone Luteinising hormone receptor Luteoma Ovary Pituitary gland Prolactinoma Testis Transgenic Tumorigenesis chorionic gonadotropin luteinizing hormone dimerization gene function gene targeting genomics nonhuman phenotype priority journal receptor binding review signal transduction Animals Chorionic Gonadotropin Gene Expression Genitalia Humans Luteinizing Hormone Mice Mice, Knockout Phenotype
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_03037207_v260-262_n_p255_Ahtiainen
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

Ejemplares similares

Phenotypic characterisation of mice with exaggerated and missing LH/hCG action
Publicado: (2007)

Genetically modified mouse models in studies of luteinising hormone action
por: Huhtaniemi, I., et al.

Genetically modified mouse models in studies of luteinising hormone action
Publicado: (2006)

Mouse models of altered gonadotrophin action: Insight into male reproductive disorders
por: Jonas, K.C., et al.

Mouse models of altered gonadotrophin action: Insight into male reproductive disorders
Publicado: (2014)

Multiple sites of tumorigenesis in transgenic mice overproducing hCG
por: Huhtaniemi, I., et al.

What have gonadotrophin overexpressing transgenic mice taught us about gonadal function?
Publicado: (2005)

What have gonadotrophin overexpressing transgenic mice taught us about gonadal function?
por: Rulli, S.B., et al.

Association between GNRHR, LHR and IGF1 polymorphisms and timing of puberty in male Angus cattle
por: Lirón, Juan Pedro, et al.
Publicado: (2012)

Effect of human gonadotropins on spermiation and androgen biosynthesis in the testis of the toad Bufo arenarum (Amphibia, Anura)
por: Pozzi, Andrea Gabriela, et al.
Publicado: (2006)

Effect of human gonadotropins on spermiation and androgen biosynthesis in the testis of the toad Bufo arenarum (Amphibia, Anura)
por: Pozzi, A.G., et al.

Animal models for aberrations of gonadotropin action
Publicado: (2011)

Animal models for aberrations of gonadotropin action
por: Peltoketo, H., et al.

Multiple sites of tumorigenesis in transgenic mice overproducing hCG
Publicado: (2005)

Activation of the cAMP cascade by steroidogenic hormones and glucagon in the pathogenic fungus Candida albicans
por: Paveto, María Cristina, et al.
Publicado: (1991)

Activation of the cAMP cascade by steroidogenic hormones and glucagon in the pathogenic fungus Candida albicans
por: Paveto, C., et al.

Evidence for different gonadotropin-releasing hormone response sites in rat ovarian and pituitary cells
Publicado: (2004)

Evidence for different gonadotropin-releasing hormone response sites in rat ovarian and pituitary cells
por: Mongiat, L.A., et al.

Ontogenic studies of the neural control of adenohypophyseal hormones in the rat: Gonadotropins
Publicado: (1990)

Ontogenic studies of the neural control of adenohypophyseal hormones in the rat: Gonadotropins
por: Becú-Villalobos, D., et al.

Effect of bilateral denervation of the immature rat testis on testicular gonadotropin receptors and in vitro
Publicado: (1993)

Effect of bilateral denervation of the immature rat testis on testicular gonadotropin receptors and in vitro
por: Campos, M.B., et al.

Enhanced LH action in transgenic female mice expressing hCGβ-subunit induces pituitary prolactinomas; the role of high progesterone levels
por: Ahtiainen, P., et al.

Fetal but not adult Leydig cells are susceptible to adenoma formation in response to persistently high hCG level: A study on hCG overexpressing transgenic mice
por: Ahtiainen, P., et al.

Elevated hypothalamic aromatization at the onset of precocious puberty in transgenic female mice hypersecreting human chorionic gonadotropin: Effect of androgens
por: Gonzalez, B., et al.

Immunohistochemical study of pituitary cells in wild and captive Salminus hilarii (Characiformes: Characidae) females during the annual reproductive cycle
Publicado: (2013)

Immunohistochemical study of pituitary cells in wild and captive Salminus hilarii (Characiformes: Characidae) females during the annual reproductive cycle
por: Honji, R.M., et al.

Elevated hypothalamic aromatization at the onset of precocious puberty in transgenic female mice hypersecreting human chorionic gonadotropin: Effect of androgens
Publicado: (2014)

High correlation between prolactinemia, 125-I hLH binding and progesterone secretion by an experimental luteoma
Publicado: (1984)

High correlation between prolactinemia, 125-I hLH binding and progesterone secretion by an experimental luteoma
por: Lux, V.A.R., et al.

Enhanced LH action in transgenic female mice expressing hCGβ-subunit induces pituitary prolactinomas; the role of high progesterone levels
Publicado: (2010)

Measurement of specific radioactivities in labelled hormones by self-displacement analysis
Publicado: (1983)

Measurement of specific radioactivities in labelled hormones by self-displacement analysis
por: Calvo, J.C., et al.

α-Difluoromethylornithine modifies gonadotropin-releasing hormone release and follicle-stimulating hormone secretion in the immature female rat
Publicado: (1997)

α-Difluoromethylornithine modifies gonadotropin-releasing hormone release and follicle-stimulating hormone secretion in the immature female rat
por: Thyssen, S.M., et al.

Fetal but not adult Leydig cells are susceptible to adenoma formation in response to persistently high hCG level: A study on hCG overexpressing transgenic mice
Publicado: (2005)

Effect of a gonadotropin-releasing hormone agonist on luteinizing hormone receptors and steroidogenesis in ovarian cells
Publicado: (1993)

Effect of a gonadotropin-releasing hormone agonist on luteinizing hormone receptors and steroidogenesis in ovarian cells
por: Guerrero, H.E., et al.

Sperm production, testicular size, serum gonadotropins and testosterone levels in Merino and Corriedale breeds
Publicado: (1999)

Sperm production, testicular size, serum gonadotropins and testosterone levels in Merino and Corriedale breeds
por: Fernandez-Abella, D., et al.