Real-time vascular response assessment by means of a dual pressure-diameter device: A preliminary study
Introduction: Vascular reactivity (VR) can be defined as the arterial ability to react to vasoactive stimulus in terms of vasodilator or vasoconstrictor responses, where blood vessel tone is determined both by smooth muscle and endothelial functions (EF). Flow mediated dilation (FMD) and Peripheral...
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| Autores principales: | , , , , , , , , , |
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| Formato: | CONF |
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| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_0277786X_v10160_n_p_PerezLopez |
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| Sumario: | Introduction: Vascular reactivity (VR) can be defined as the arterial ability to react to vasoactive stimulus in terms of vasodilator or vasoconstrictor responses, where blood vessel tone is determined both by smooth muscle and endothelial functions (EF). Flow mediated dilation (FMD) and Peripheral Arterial Tonometry (PAT) measurements are recognized as the most relevant techniques for VR and EF evaluation. Objective: To design an integrated system for vascular analysis based on the limitations reported in FMD technique and incorporating PAT as a simultaneous measure. Materials and Methods: A complete software platform and a specific fastening system were proposed, in order to obtain simultaneous measurements of continuous arterial pressure (by applying the applanation tonometry technique) and continuous vessel diameter variations (by processing B-mode ultrasound images) at the same vascular site. Results: Beat to beat pressure-diameter loops were obtained, along with the assessment of stiffness indices and pulse transit time values. The volunteer who used the system felt comfortable and relaxed, unworried about making about involuntary movements Conclusion: A preliminary study was carried out using this new module designed for the acquisition, realtime processing, visualization and storage of vascular behavior related data. © 2017 SPIE. |
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