Mechanism of hexachlorobenzene-induced porphyria in rats. Effect of phenobarbitone pretreatment

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The effect of a pretreatment with phenobarbitone (PB) on the porphyrinogenic action exerted by hexachlorobenzene (HCB) was examined in female rats. Kinetic studies of enzyme function after HCB poisoning showed that porphyrinogen carboxy-lyase was the only enzyme of haem biosynthesis that markedly lo...

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Autores principales:	Wainstok de Calmanovici, R., Del Rios de Molina, C.M., Taira de Yamasato, M.C.
Formato:	JOUR
Materias:	hexachlorobenzene liver enzyme phenobarbital animal experiment drug intoxication drug mechanism hepatic porphyria intoxication liver nonhuman porphyria rat Animalia
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_02646021_v218_n3_p753_WainstokdeCalmanovici
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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