Apotransferrin decreases the response of oligodendrocyte progenitors to PDGF and inhibits the progression of the cell cycle

In the CNS, transferrin (Tf) is expressed by the oligodendroglial cells (OLGcs) and is essential for their development. We have previously shown that apotransferrin (aTf) accelerates maturation of OLGcs in vivo as well as in vitro. The mechanisms involved in this action appear to be complex and have...

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Detalles Bibliográficos
Autores principales: Paez, P.M., Garcia, C.I., Soto, E.F., Pasquini, J.M.
Formato: JOUR
Materias:
Cell cycle
Cyclins
Oligodendrocyte
PDGF
Transferrin
apotransferrin
cyclin D
cyclin dependent kinase 2
cyclin dependent kinase 4
cyclin E
protein p27
article
cell cycle
cell cycle G1 phase
cell cycle S phase
cell differentiation
cell maturation
cell structure
central nervous system
controlled study
evaluation
flow cytometry
human
human cell
oligodendroglia
priority journal
protein expression
stem cell
Animals
Antimetabolites
Apoproteins
Blotting, Western
Bromodeoxyuridine
Cell Cycle
Cell Differentiation
Cyclin-Dependent Kinases
Depression, Chemical
DNA
Electrophoresis, Polyacrylamide Gel
Flow Cytometry
G1 Phase
Immunohistochemistry
Oligodendroglia
Platelet-Derived Growth Factor
Rats
S Phase
Stem Cells
Tetrazolium Salts
Thiazoles
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_01970186_v49_n4_p359_Paez
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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