Inhibition of cytochrome P-450 C17 enzyme by a GnRH agonist in ovarian follicles from gonadotropin-stimulated rats

Our objective was to study the direct action of a GnRH-I agonist, leuprolide acetate (LA), on ovarian steroidogenesis in preovulatory follicles obtained from equine chorionic gonadotropin (eCG)-treated rats. Previously, we have demonstrated an inhibitory effect of LA on steroidogenesis and follicula...

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Detalles Bibliográficos
Autores principales: Irusta, G., Parborell, F., Tesone, M.
Formato: JOUR
Materias:
Follicle
Gonadotropin-releasing hormone agonist
Ovary
Steroidogenesis
androgen
androsterone
cytochrome P450
gonadorelin
gonadorelin agonist
gonadotropin
leuprorelin
steroidogenic acute regulatory protein
animal experiment
article
controlled study
enzyme inhibition
female
gene expression
immunohistochemistry
nonhuman
ovary follicle
priority journal
progesterone blood level
rat
reverse transcription polymerase chain reaction
steroidogenesis
Western blotting
Androsterone
Animals
Blotting, Western
Female
Gonadotropin-Releasing Hormone
Gonadotropins, Equine
Horses
Immunohistochemistry
Leuprolide
Ovarian Follicle
Phosphoproteins
Progesterone
Rats
Rats, Sprague-Dawley
Reverse Transcriptase Polymerase Chain Reaction
RNA
Steroid 17-alpha-Hydroxylase
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_01931849_v292_n5_pE1456_Irusta
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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