Metabolic selective pressure stabilizes plasmids carrying biosynthetic genes for reduced biochemicals in Escherichia coli redox mutants

Several biotechnological processes rely on the utilization of high-copy-number plasmids for heterologous gene expression, and understanding the interactions between plasmid DNA and bacterial hosts is highly relevant for bioprocess optimization. We assessed metabolic modifications and physiological c...

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Autores principales: Nikel, P.I., Pettinari, M.J., Galvagno, M.A., Méndez, B.S.
Formato: JOUR
Materias:
DNA
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_01757598_v88_n2_p563_Nikel
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