Correlation between synaptogenesis and the PTEN phosphatase expression in dendrites during postnatal brain development

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The PTEN (phosphatase and tensin homolog deleted on chromosome 10) tumor suppressor gene codifies a lipid inositol 3′-phosphatase that negatively regulates cell survival mediated by the phosphatidyl inositol 3′ kinase (PIP3-kinase)-protein kinase B/Akt signaling pathway. Recently, PIP3-kinase was in...

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Detalles Bibliográficos
Autores principales: Perandones, C., Costanzo, R.V., Kowaljow, V., Pivetta, O.H., Carminatti, H., Radrizzani, M.
Formato: JOUR
Materias:
Cellular and molecular biology
Cerebellum
Dendrites
Phosphatidylinositol phosphatase
PTEN
Staining, tracing, and imaging techniques
Synaptogenesis
Weaver
phosphatase
phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase
animal cell
animal tissue
article
brain cortex
brain development
cell survival
cerebellum
controlled study
correlation analysis
dendrite
granule cell
hippocampus
mouse
nerve fiber
nonhuman
olfactory bulb
polarization
postnatal development
priority journal
protein analysis
protein expression
Purkinje cell
sequence homology
synaptogenesis
1-Phosphatidylinositol 3-Kinase
Animals
Brain
Catalytic Domain
Cell Polarity
Immunohistochemistry
Mice
Mice, Inbred C57BL
Mice, Neurologic Mutants
Peptide Fragments
Protein-Serine-Threonine Kinases
Protein-Tyrosine-Phosphatase
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-akt
PTEN Phosphohydrolase
Signal Transduction
Statistics
Synapses
Tissue Distribution
Tumor Suppressor Proteins
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_0169328X_v128_n1_p8_Perandones
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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