Requirement of cholesterol in the viral envelope for dengue virus infection

•Cholesterol in the virion envelope is essential for dengue virus infectivity.•The four dengue serotypes are similarly inactivated by cholesterol-extracting drugs.•Dengue virus uncoating is blocked in infection with cholesterol-depleted virions.•Virion treatment with exogenous cholesterol exert also...

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Detalles Bibliográficos
Autores principales: Carro, A.C., Damonte, E.B.
Formato: JOUR
Materias:
Cholesterol
Dengue virus
Infectivity
Methyl-beta-cyclodextrin
Viral envelope
Virucidal activity
capsid protein
cholesterol
methyl beta cyclodextrin
nystatin
protein
virus protein
virus RNA
animal cell
article
cell membrane
controlled study
cytoplasm
dengue
endosome
host cell
human
human cell
nonhuman
priority journal
RNA synthesis
serotype
virion
virus attachment
virus envelope
virus expression
virus infectivity
virus nucleocapsid
Cell Line
Dengue Virus
Humans
Membrane Lipids
Virus Internalization
Bovinae
Miridae
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_01681702_v174_n1-2_p78_Carro
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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