Progesterone regulates the expression and activity of two mouse isoforms of the glycoprotein folding sensor UDP-Glc: Glycoprotein glucosyltransferase (UGGT)

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UDP-Glucose:glycoprotein glucosyltransferase (UGGT) is a central component of the endoplasmic reticulum (ER) glycoprotein-folding quality control system, which prevents the exit of partially folded species. UGGT activity can be regulated by the accumulation of misfolded proteins in the ER, a stimulu...

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Detalles Bibliográficos
Autores principales: Prados, M.B., Caramelo, J.J., Miranda, S.E.
Formato: JOUR
Materias:
DJN
Endoplasmic reticulum quality control
Folding
P4
Progesterone
UDP-Glc: glycoprotein glucosyltransferase
UGGT
UPR
glucosyltransferase
glycoprotein
progesterone
UDP glucose glycoprotein glucosyltransferase
unclassified drug
animal experiment
animal model
article
cell proliferation
cellular distribution
controlled study
endoplasmic reticulum
enzyme activity
gene expression
gene silencing
hormonal regulation
hybridoma
hybridoma cell culture
intracellular signaling
mouse
nonhuman
priority journal
protein analysis
protein expression
protein folding
protein function
protein synthesis
quality control
unfolded protein response
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_01674889_v1833_n12_p3368_Prados
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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