Alterations in the intestine of Patagonian silverside (Odontesthes hatcheri) exposed to microcystin-LR: Changes in the glycosylation pattern of the intestinal wall and inhibition of multidrug resistance proteins efflux activity

Accumulation and toxicity of cyanobacterial toxins, particularly microcystin-LR (MCLR) have been extensively studied in fish and aquatic invertebrates. However, MCLR excretion mechanisms, which could reduce this toxin's effects, have received little attention. The Patagonian silverside, Odontes...

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Detalles Bibliográficos
Autores principales:	Bieczynski, F., Torres, W.D.C., Painefilu, J.C., Castro, J.M., Bianchi, V.A., Frontera, J.L., Paz, D.A., González, C., Martín, A., Villanueva, S.S.M., Luquet, C.M.
Formato:	JOUR
Materias:	Abcc transporters Cyanotoxin Glycoconjugates Intestinal sacs Lectin-histochemistry Multixenobiotic resistance Odontesthes hatcheri 2,4 dinitrophenyl s glutathione agglutinin calcein concanavalin A glutathione derivative glycoconjugate lectin microcystin LR multidrug resistance protein phosphoprotein phosphatase 1 unclassified drug verlukast dolichos biflorus agglutinin fluorescein derivative glutathione microcystin plant lectin propionic acid derivative quinoline derivative water pollutant cyanobacterium drug resistance ecotoxicology fish inhibition phytotoxicity protein toxin trophic structure animal experiment animal tissue Article Atherinopsidae body mass chemical composition concentration response controlled study Dolichos Dolichos biflorus enzyme activity female glycosylation histochemistry intestine cell intestine wall male nonhuman priority journal protein transport Triticum vulgaris wheat animal drug effects fluorescence microscopy intestine mucosa metabolism Smegmamorpha toxicity transport at the cellular level Argentina elongata Cyanobacteria Invertebrata Triticum aestivum Animals Biological Transport Concanavalin A Fluoresceins Glutathione Glycosylation Intestinal Mucosa Microcystins Microscopy, Fluorescence Multidrug Resistance-Associated Proteins Plant Lectins Propionates Quinolines Water Pollutants, Chemical
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_0166445X_v178_n_p106_Bieczynski
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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