Cytogenetic findings, Trp53 mutations, and hormone responsiveness in a medroxyprogesterone acetate induced murine breast cancer model

Medroxyprogesterone acetate (MPA)-induced mammary carcinomas express high levels of estrogen (ER) and progesterone receptors (PR) and when transplanted in syngeneic mice they show a progestin-dependent (PD) growth pattern. By successive transplantation, progestin-independent (PI) variants were gener...

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Detalles Bibliográficos
Autores principales: Fabris, V.T., Benavides, F., Conti, C., Merani, S., Lanari, C.
Formato: JOUR
Materias:
estrogen receptor
gestagen
medroxyprogesterone acetate
progesterone receptor
aneuploidy
animal cell
animal model
animal tissue
article
breast cancer
cancer growth
cancer transplantation
chromosomal instability
chromosome 16
chromosome 3
chromosome 4
chromosome 6
chromosome 7
chromosome mutation
chromosome number
chromosome translocation
controlled study
cytogenetics
diploidy
female
gene mutation
hormone response
mouse
mouse strain
nonhuman
point mutation
priority journal
single strand conformation polymorphism
tetraploidy
triploidy
tumor
X chromosome
Aneuploidy
Animals
Chromosome Banding
Female
Genes, p53
In Situ Hybridization, Fluorescence
Mammary Neoplasms, Experimental
Medroxyprogesterone 17-Acetate
Mice
Mice, Inbred BALB C
Neoplasms, Hormone-Dependent
Point Mutation
Tryptophan
Murinae
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_01654608_v161_n2_p130_Fabris
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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