Amyotrophic lateral sclerosis IgG-treated neuromuscular junctions develop sensitivity to L-type calcium channel blocker

In order to search for early changes induced by the application of human immunoglobulin G (IgG) on motor nerve terminals, IgG from patients with amyotrophic lateral sclerosis (ALS) and control subjects was injected subcutaneously into the levator auris muscle of mice. A week or a month after the las...

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Detalles Bibliográficos
Autores principales: Fratantoni, S.A., Weisz, G., Pardal, A.M., Reisin, R.C., Uchitel, O.D.
Formato: JOUR
Materias:
Amyotrophic lateral sclerosis
Calcium channels
Neuromuscular junction
Nitrendipine
Transmitter release
calcium channel blocking agent
immunoglobulin G
nitrendipine
adult
aged
amyotrophic lateral sclerosis
animal cell
animal model
animal tissue
article
calcium transport
clinical article
controlled study
female
human
human cell
human tissue
immunotherapy
male
mouse
nerve cell necrosis
neurotransmitter release
nonhuman
priority journal
protein expression
voltage clamp
Adult
Aged
Animals
Calcium Channel Blockers
Calcium Channels, L-Type
Evoked Potentials
Female
Humans
Immunoglobulin G
Male
Mice
Middle Aged
Motor Neuron Disease
Muscle, Skeletal
Neuromuscular Junction
omega-Agatoxin IVA
omega-Conotoxin GVIA
Reference Values
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_0148639X_v23_n4_p543_Fratantoni
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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