Lipase-catalyzed mono-O-acylation of dithiothreitol and dithioerythritol
Mono-O-acyl derivatives of dithiothreitol and dithioerythritol were obtained in 40-60% yield, through a lipase-catalyzed transesterification in organic media. Reactions were conducted in neutral conditions at moderate temperature, with or without solvent. Candida antarctica lipase resulted the most...
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| Autores principales: | , , |
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| Formato: | JOUR |
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| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_01415492_v20_n3_p275_Iglesias |
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| Sumario: | Mono-O-acyl derivatives of dithiothreitol and dithioerythritol were obtained in 40-60% yield, through a lipase-catalyzed transesterification in organic media. Reactions were conducted in neutral conditions at moderate temperature, with or without solvent. Candida antarctica lipase resulted the most efficient biocatalyst (yields over 60%) when working without solvent. |
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