Establishment of cell-based transposon-mediated transgenesis in cattle

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Transposon-mediated transgenesis is a well-established tool for genome modification in small animal models. However, translation of this active transgenic method to large animals warrants further investigations. Here, the piggyBac (PB) and sleeping beauty (SB) transposon systems were assessed for st...

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Detalles Bibliográficos
Autores principales: Alessio, A.P., Fili, A.E., Garrels, W., Forcato, D.O., Olmos Nicotra, M.F., Liaudat, A.C., Bevacqua, R.J., Savy, V., Hiriart, M.I., Talluri, T.R., Owens, J.B., Ivics, Z., Salamone, D.F., Moisyadi, S., Kues, W.A., Bosch, P.
Formato: JOUR
Materias:
Cattle
PiggyBac
Sleeping beauty
Transgenesis
Transposon
transposase
transposon
animal
bovine
cell line
cell nucleus transplantation
fibroblast
gene vector
genetic transfection
genetics
transgenic animal
Animals
Animals, Genetically Modified
Cell Line
DNA Transposable Elements
Fibroblasts
Genetic Vectors
Nuclear Transfer Techniques
Transfection
Transposases
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_0093691X_v85_n7_p1297_Alessio
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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