Induction of Glutathione S-transferase Activity in Triatoma infestans

Several synthetic pesticides and allelochemicals used to treat Triatoma infestans adults by topic application showed some degree of cytosolic glutathione S-transferase (GST) induction. General inducers of detoxication systems such as phenobarbital and 3-methylcholantrene topically applied on T. infe...

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Detalles Bibliográficos
Autores principales: Sívori, J.L., Casabé, N., Zerba, E.N., Wood, E.J.
Formato: JOUR
Materias:
Glutathione S-transferase
Induction
Triatoma infestans
Hexapoda
Insecta
glutathione transferase
animal
article
biosynthesis
drug effect
enzyme induction
enzymology
male
Triatoma
ultraviolet spectrophotometry
Animals
Enzyme Induction
Glutathione Transferase
Male
Spectrophotometry, Ultraviolet
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00740276_v92_n6_p797_Sivori
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
Descripción
Sumario:Several synthetic pesticides and allelochemicals used to treat Triatoma infestans adults by topic application showed some degree of cytosolic glutathione S-transferase (GST) induction. General inducers of detoxication systems such as phenobarbital and 3-methylcholantrene topically applied on T. infestans resulted in no GST induction. Meanwhile, general insecticide Synergist such as piperonyl butoxide (160 μg/insect) increased the GST-activity in the range of 120-140%. Insects injected with reduced glutathione (300 mg/insect) presented at the forth day elevated GST activity.

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